My Global Hustle

An artificial heart and its lightweight power drive. A better airline for Brazil. Chocolate from Madagascar and a soccer shirt made of plastic water bottles. A fashion leader escaping its pattern, a smelter, and that little coupon startup in Chicago that's suddenly worth billions. All this from one simple word: innovation.

The 50 companies on our 2011 list have chosen a unique path. Today's business landscape is littered with heritage companies whose CEOs battle their industry's broken model with inertia, layoffs, lawsuits — anything that squeezes pennies and delays the inevitable. How many of these companies will be dominant in 2025? Few.

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via Jeff Taylor